308nm xenon chloride laser (XeCl laser) 308nm excimer laser, also known as xenon laser, was approved by the FDA in 2000 for psoriasis treatment. 308nm excimer laser wavelength is similar to NB-UVB (31Inm), but traditional UVB is multi-frequency continuous non-coherent light, excimer laser is single-frequency coherent light, the two pulses are different. The frequency is different, in the treatment of vitiligo excimer laser shows better efficacy than NB-UVB [In recent years, some people try to use 308nm xenon laser for the treatment of stable focal vitiligo and get better results. 308nm excimer laser is the latest method for the treatment of vitiligo, compared with other light therapy including narrow-spectrum UVB, the laser is more penetrating at the same energy and can penetrate up to 1.5 In addition, it is flexible and can be used to treat focal lesions, especially in the skin folds; because of its higher selectivity, it only targets the lesions and rarely affects the normal skin around the lesions, thus making it possible to further improve the efficacy by applying large doses; at the same time, it can shorten the treatment time, reduce the total UV exposure, and reduce the possibility of skin cancer. The 308nm excimer laser is expected to be a fast and effective new method for vitiligo treatment, and is a better choice for the treatment of vitiligo, especially limited vitiligo, combined with other treatment methods to further improve the efficacy.