Cephalosporin refers to cephalosporin antibiotics, azithromycin is a macrolide antibiotic, bronchopneumonia with which drug is good can not be generalized, need to be based on the susceptibility of pathogens, combined with the patient’s own choice of drug sensitivity. Bronchopneumonia is an infectious disease, caused by bacteria, viruses, Mycoplasma pneumoniae and other infections. Cephalosporin and azithromycin are both broad-spectrum antibiotics. Both antibiotics can be chosen when considering bronchitis caused by bacterial infections, but azithromycin is more effective when considering mycoplasma and chlamydia infections. For the choice of antibiotics, firstly, the choice should be combined with the sensitivity of the pathogen, and secondly, the choice should be combined with the patient’s own sensitivity to the drug, which needs to be judged according to the bacterial culture and drug sensitivity test. It should be noted that after taking cephalosporins may appear headache, nausea, abdominal pain, diarrhea, rash and other adverse reactions, you can not drink alcohol during the medication, and those who are allergic to cephalosporins should not take it. Adverse reactions such as abdominal pain, nausea, and vomiting may occur during the administration of azithromycin. People with known allergy to Azithromycin should not take it. Bronchitis patients are advised to go to the regular hospital in time, choose the right drugs according to personal conditions, avoid unauthorized use of drugs, otherwise not only fail to achieve results, but also affect the patient’s health. Drugs need to be used under the guidance of a physician.