Commonly used medications for diabetic foot include hypoglycemic drugs, nutritive nerve drugs, circulatory improvement drugs, antibiotics, etc., such as alpha lipoic acid, Epalrestat, Prostaglandin, etc., which need to be used according to the condition as prescribed by the doctor. 1. Antihyperglycemic drugs: Take antihyperglycemic drugs such as acarbose or insulin injections as prescribed by the doctor, to control the blood sugar steadily will also help to treat diabetic foot. 2. Nutritional nerve drugs: α-lipoic acid can improve nerve sensory abnormality and nerve conduction abnormality; Epalrestat can slow down the progression of diabetic peripheral neuropathy, and can be used in combination with α-lipoic acid. 3. Drugs to improve circulation: when accompanied by lower limb vascular lesions, prostaglandin and other treatments can be used as prescribed by the doctor, which can improve circulation. 4. Antibiotics: for diabetic foot patients with infections and ulcers, penicillin and metronidazole can be chosen. Patients diagnosed with diabetic foot should actively cooperate with the doctor’s treatment, and should not self-medication.