Cerebral thrombosis according to the different time windows, static drugs are different, if within 4.5 hours, can be static atipase thrombolytic drugs, if for the late stage can be static to improve the circulation of drugs, such as butylphthalide sodium chloride injection and scavenging of free radicals drugs, such as edaravone injection and so on. The principle of treatment of cerebral thrombosis is to rapidly restore blood supply to the ischemic area, if there is no contraindication to thrombolysis within 4.5 hours of the golden period, should be actively thrombolytic therapy, which can promote cerebral metabolism, control of cerebral edema and the protection of brain cells, static thrombolysis of commonly used drugs are recombinant tissue-type fibrinolytic plasminogen activator, such as alteplase. If the golden period has been missed, in addition to oral aspirin, clopidogrel, atorvastatin, etc., static drugs are mainly to improve the circulation in the ischemic area, promote collateral circulation drugs, such as butylphthalide sodium chloride injection and scavenging of free radicals, cerebral protection drugs, such as edaravone injection. Those who have cerebral thrombosis should consult a doctor in time and standardize the treatment under the doctor’s guidance.