Acute and chronic skin lesions in diabetes are diverse and are closely related to the patient’s elevated blood glucose and decreased local resistance. Most diabetic skin lesions are not unique to diabetic patients. However, these lesions have a much greater chance of occurring than in non-diabetics and include: 1. Pruritus. In diabetic patients is very common, which is the result of high blood sugar stimulation of nerve endings, vulva because of the stimulation of urine sugar and local infection, itching is more common, some people found pruritus in diabetic patients incidence of up to 7%-43%; 2, skin fungal infections. Fungal infections account for the most common skin lesions in diabetes, far more than in non-diabetics, such as tinea cruris, tinea pedis, tinea nail, ringworm, tinea corporis, and vulvar candidiasis. 3. Bacterial skin infections. Such as boils and carbuncles are much more common in diabetic patients than in non-diabetic patients, and often serve as a clue to detect diabetes; 4. Anterior tibial pigmentation. Mostly seen in male diabetic patients, occurring on the front side of the calf, the skin may start with erythema, blistering, purpura, erosion or ulceration, and then gradually form a variable number of brown spots of different shapes, without pain or itching, which can fade on their own after 12 years; 5. Diabetic macules. It is a rare but characteristic skin lesion in diabetic patients, no obvious cause before the onset, suddenly appearing in the extremities of the extremities of large blisters, varying in size from 0.5-10 cm, the walls of the blisters are tense, thin and transparent, containing clear fluid, similar to the blisters of burns, the conscious symptoms are not obvious, l to 2 weeks after the blisters disappear on their own, leaving no trace. The treatment of diabetic skin lesions also includes diabetic control, local treatment and, if necessary, systemic treatment.