Sperm-coated antibody IgG test (mixed antiglobulin reaction) is used to screen for immune infertility. The presence of antibodies on the sperm surface can reduce sperm motility, block the passage of sperm through cervical mucus, and also prevent sperm from binding to the oocyte resulting in impaired fertilization. Sperm-coated antibodies are a typical and specific correlate of immune infertility. When the MAR result is abnormal, the diagnosis of immune infertility may be made, but this diagnosis must be confirmed by other tests (sperm-cervical mucus contact test, sperm-cervical mucus capillary test). Mixed agglutination reaction (MAR). The anti-IgG antiserum binds both to IgG antibodies present on the sperm surface and to IgG encapsulated on latex particles, thus forming a sperm IgG antibody-anti-IgG-IgG encapsulated latex particle complex, which is attached to the sperm surface and swims with the sperm. Microscopic observation of latex particles attached to the surface of the swimming sperm is considered to indicate the presence of IgG-coated antibodies in the sperm. Treatment: 1. Adrenocorticotropic hormone application: (1) low-dose continuous therapy; (2) high-dose intermittent therapy; (3) cycle therapy; (4) diaphragm week decreasing therapy. 2. Testosterone rebound therapy; 3. In vitro treatment of semen: sperm washing, etc.; 4. Chinese herbal medicine.
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