Sore throat needs to improve the blood routine, laryngoscopy, sputum smear or pharyngeal swab, etc., to clarify the diagnosis. Sore throat is considered to have acute upper respiratory tract infection, complete blood routine can be initially determined whether the pathogen is more inclined to bacterial or viral, bacterial infections can be white blood cell count and neutrophil percentage and count increase. In viral infections, there is usually an increase in the number of lymphocytes and monocytes. Laryngoscopy can observe the redness and swelling of the pharynx and the proliferation of lymphoid follicles in the pharynx. It can also examine the pharynx to see if there are any foreign bodies and neoplastic organisms, such as pharyngeal abscess, which can help to diagnose the disease and determine the condition. Sputum smear or pharyngeal swab can clarify the nature of the infectious agent. Sputum smear or sputum culture, etc., can clarify the infecting organisms and, based on the results, choose the appropriate antibiotics. Pharyngeal swabs can clarify or rule out associated viruses and help guide treatment. Sore throat may have multiple etiologies, and prompt medical attention and standardized treatment are recommended.