The life expectancy of cirrhotic patients after spleen removal is the same as that of ordinary cirrhotic patients. The main purpose of spleen removal treatment for cirrhotic patients is to reduce portal vein pressure and to prevent the next rupture and bleeding of esophagogastric fundic varices. After splenectomy, platelet increase can occur, and the formation of venous thrombosis must be prevented, especially the formation of abdominal artery thrombosis, if there is a serious thrombosis, it may be life-threatening because it is very easy to develop intestinal necrosis. After splenectomy treatment, cirrhotic patients need to apply low-molecular heparin, warfarin and other blood-activating, stasis-clearing and anticoagulant drugs if necessary to try to prevent the formation of thrombosis. After splenectomy for cirrhosis, pseudobullets still exist, which may lead to increased portal vein pressure and may cause variceal rupture and bleeding again, which should be prevented.