Nuclear jaundice is what is referred to as bilirubin encephalopathy. This condition, if treated aggressively, does not cause cerebral palsy in all children. But if it is not treated aggressively, this is the time to leave the sequelae and the possibility of cerebral palsy. In general, nuclear jaundice occurs mainly because the concentration of unconjugated bilirubin in the serum is too high and passes through the newborn’s underdeveloped blood-brain barrier, causing necrosis of nerve cells near the basal nucleus and resulting in encephalopathy. Its main manifestations are lethargy, hyporesponsiveness, and weakness of sucking in the child. During the spastic phase, there can be convulsions, coracoacusis, fever, etc. During the recovery period, the feeding will improve, the number of convulsions will decrease, coracoacusis will gradually disappear, and muscle tone will return to normal. If there is no active treatment at this time, the child may develop to the posterior phase. The main manifestation of the posterior phase is the appearance of frequent involuntary, purposeless movements, impaired upward eye movements, and the formation of more obvious sunset eyes. Hearing impairment, enamel hypoplasia, and green or dark brown teeth. There is also the possibility of cerebral palsy, mental retardation, and convulsions.