Most people who take anti-inflammatory drugs will experience nausea, vomiting and other upper gastrointestinal discomfort symptoms, which are adverse drug reactions, patients do not need to be nervous, especially quinolones or clarithromycin and other drugs, gastrointestinal reactions are relatively large, while cephalosporins may be relatively small. It is recommended that anti-inflammatory drugs or other antibiotics are best taken orally after meals to alleviate gastrointestinal discomfort. Of course, all anti-inflammatory drugs need to be weighed against the pros and cons before they are used, because the abuse of antibiotics may cause bacterial resistance. Before the use of drugs, especially the use of antibiotics need to cooperate with the doctor to do the relevant tests, such as blood routine, blood biochemistry, stool routine, C-reactive protein, etc., to help understand the specific infection, if indeed reached the use of antibiotics indications, only then can follow medical advice to use antibiotic treatment.