Portal vein cavernous degeneration is a complete or partial embolization of the main trunk or branches of the portal vein, followed by the formation of collateral veins or recanalization of the lumen. Cirrhosis can cause portal vein cavernous degeneration. Portal vein cavernous degeneration is divided into two categories: primary and secondary. In secondary cases, the normal portal venous system is blocked by various pathogenic factors, resulting in increased portal venous pressure, establishment of collateral circulation, and recanalization of the portal vein. In PVCT, long-term portal vein obstruction leads to the establishment of hepatic collateral circulation. This leads to esophagogastric fundic varices, rupture and bleeding, splenic stasis and enlargement, and hypersplenism. Since the hepatic arterial blood supply is not affected, the liver itself may not be significantly altered. Clinical manifestations: epigastric distention, pain and discomfort, repeated vomiting of blood, black stool, hemorrhagic shock, mild to moderate splenomegaly and hypersplenism may occur. Barium esophageal X-ray shows varices in the esophagus. Treatment of PVCT 1.Medical treatment: symptomatic treatment is the main treatment. If the clinical symptoms are not obvious or a small amount of bleeding, protect the esophagus and gastric mucosa mainly, eat less irritating and rough food to reduce the gastric mucosa lesion and reduce the chance of vascular rupture. In the acute stage with thrombosis, thrombolytic therapy is given, but there is a risk of bleeding, and thrombolytic therapy is not recommended in the chronic stage. Endoscopic treatment can be considered in case of GI bleeding, but it is easy to recur because the portal vein lesion still exists. 2.Surgical treatment: splenectomy + portal vein shunt or cardia-gastric fundoplication is the surgical method, but the efficacy is not very satisfactory, in addition to the large trauma, the portal vein cannot be opened during the dissection surgery, and the shunt surgery is complicated, so the clinical application is small. 3.Interventional treatment: It is a new technology in recent years. In the past, interventional and surgical treatment of PVCT was contraindicated, but with the treatment of portal hypertension, cirrhosis, gastrointestinal bleeding and hypersplenism, we have accumulated a lot of experience and applied percutaneous hepatic penetration technology, portal stent technology and TIPSS technology to PVCT, which has successfully cured dozens of patients and reduced portal vein pressure, so that the patients’ ascites disappeared and bleeding stopped.