There are many causes of thigh pain, and different treatment options are needed depending on the specific cause. Common causes include acute lymphadenitis, sebaceous cyst with infection, incarcerated femoral hernia and myofascial strain, prostatitis or testicular disease. For acute lymphadenitis and sebaceous cysts with infection, sensitive antibacterial drugs such as first-generation cephalosporins, macrolides and penicillins, commonly used are amoxicillin, roxithromycin and cefadroxil, and if necessary, intravenous drips should be used. If the local redness and pain are obvious, magnesium sulfate can be applied as a wet compress, and the abscess can be drained in time to avoid damaging the large blood vessels at the root of the thigh, such as the femoral artery, and to prevent lymphatic leakage. Once detected, patients with an embedded femoral hernia should be treated with surgery because of its tendency to cause necrosis of the contents. If necrosis is not present, a tension-free hernia repair can be performed. If necrosis is present, only the necrotic tissue, such as the greater omentum or the intestinal canal, should be removed and not repaired. For patients with prostatitis, generally aseptic prostatitis can be considered oral prostate health or prostaglandin, combined with bacterial infection, also apply sensitive antibacterial drugs, such as quinolones.