Panic and palpitations caused by hyperthyroidism can be controlled by taking propranolol instead of digoxin. Propranolol is a beta-blocker that slows down the heart rate and relieves symptoms of panic palpitations; secondly, propranolol also blocks the excitatory effect of thyroid hormones on the heart. The drug should not be used in patients with asthma, allergic rhinitis, sinus bradycardia, severe atrioventricular block and low blood pressure. Adverse reactions such as bradycardia, dizziness, and abdominal pain may occur in normal people taking propranolol. Digoxin belongs to the digitalis group of drugs and can be used to lower the heart rate to improve panic symptoms, but is not used in patients with hyperthyroidism. Patients with hyperthyroidism are resistant to digoxin and are also prone to adverse effects such as nausea, vomiting, diarrhea, abdominal pain, and cardiac arrhythmias. In addition, digoxin does not have propranolol to block the excitatory effect of thyroid hormone on the heart. Digoxin is contraindicated in patients with hypertrophic heart disease, aortic stenosis, and severe atrioventricular block. Therefore, panic palpitations caused by hyperthyroidism can be controlled with propranolol. Patients with hyperthyroidism should go to the hospital in time after the occurrence of panic palpitations, follow the doctor’s instructions to take medication, avoid self-medication at home, otherwise it is easy to have adverse drug reactions.