The main types of premature ejaculation sprays are sprays such as lidocaine and proparacaine. In the treatment of premature ejaculation (PE), premature ejaculation sprays are in fact sprays made of local anesthetic drugs, such as lidocaine and proparacaine sprays. These drugs may reduce penile sensitivity and prolong intravaginal ejaculation latency time (IELT), thus improving the symptoms of PE, but these drugs (especially when used in large quantities) can have an effect on erectile function and are not used as a first-line treatment option. The most important principle in the treatment of premature ejaculation is to clarify the etiology, and common causes include, but are not limited to, penile skin hypersensitivity, psychologically related disorders (e.g., anxiety, etc.), abnormal seminal plasma magnesium levels, hyperthyroidism, and prostatitis. The use of sprays on their own without a clear cause may be less effective or even cause adverse consequences. It is recommended to seek medical treatment (urology) as soon as possible before doing the relevant treatment, under the guidance of the physician for diagnosis and treatment.