Hematological nevus is a kind of hemangioma, which can be treated with oral propranolol, glucocorticoid, sirolimus, interferon alpha and other medicines, but whether it can be eliminated or not has individual differences, and it should be handled in accordance with doctor’s prescription. 1. Propranolol: Oral propranolol can be taken for hemangioma, and short-term hospitalization is required during the application period. Attention should be paid to regular examination of biochemistry, electrocardiogram, cardiac ultrasound and local ultrasound, so as to facilitate the assessment of the efficacy of the drug and the adverse reactions. 2. Glucocorticosteroids: such as prednisone, for patients who are not suitable for propranolol treatment, during the use of the drug may have temporary effects on the child’s height, weight and blood pressure, should be closely monitored. 3. Sirolimus: Sirolimus has immunosuppressive inhibitory effect, mainly used in the treatment of junctional hemangioma. However, long-term application may lead to immunosuppression and thus complicate serious infection. 4. Interferon alpha: it is suitable for junctional hemangioma and infantile hemangioma for which drug treatment is ineffective. Interferon alpha may affect the growth and development of infants and young children, and it is not suitable for infants under 8 months of age. The use of drugs should be under the guidance of medical professionals. If drug treatment is ineffective, surgery or physical therapy is feasible.