Toothpaste does not have the effect of preventing premature ejaculation, do not apply it randomly, it is recommended that the patient should actively seek medical attention, the general treatment methods are psychological treatment, drug treatment and behavioral therapy. 1. Psychological treatment: premature ejaculation and psychological factors have a correlation, by psychological factors related to premature ejaculation patients need to carry out psychological intervention to understand the problems associated with premature ejaculation, and psychological counseling for both husband and wife. 2. Medication: Pentazocine reuptake inhibitors, such as dapoxetine and fluoxetine, can be used to treat premature ejaculation; lidocaine gel can also be used externally to improve premature ejaculation and prolong the duration of sexual life. 3. Behavioral therapy: (1) Squeezing method: when a man is about to ejaculate, the woman puts her thumb on the penile ligament area, and her index and middle fingers are placed on the upper and lower part of the coronal groove margin of the penis, and gently squeezes it for 4~5 seconds, which can ease the feeling of ejaculation. The method is simple to operate, easy to grasp, and lasts 3 to 6 months to see the effect. (2) stop-motion method: this method is designed to improve the ability of men to control ejaculation, men in the imminent ejaculation to stop stimulation, will shift attention, 4 ~ 5 seconds after the sexual stimulation again, that is, stimulation – stop – and then stimulation form. Such repeated training can improve the male ejaculation threshold. (3) Functional-sexual therapy: mainly by adjusting the pelvic movement to reduce muscle tension, slow down the breathing rate and use abdominal breathing to make the process of sexual intercourse longer. (4) Surgery: Surgery can be chosen from dorsal penile nerve dissections and so on. There are many other methods can be used for premature ejaculation in boys, it is recommended that such patients go to regular hospitals, cooperate with the doctor to complete the relevant examinations, and active treatment.