Tinea pedis needs to be treated with topical and internal antifungal medications, and antibiotics are also needed for combined bacterial infections. The impregnated tinea pedis is more likely to occur between the toes, especially if the feet are sweaty and wear shoes with poor breathability. The manifestation is that there are stained whitish lesions between the toes, the epidermis is easy to peel off, and after peeling off, it exposes moist and bright red wounds, usually with intense itching, and may be complicated by bacterial infections, which manifests obvious odor. For macerated erosion type tinea pedis, 3% borax solution and 1% isacridine solution can be used externally as wet compresses, and econazole nitrate cream and miconazole nitrate cream can also be used for treatment. At the same time can be taken internally terbinafine, itraconazole and other antifungal drugs for treatment. If accompanied by bacterial infection, can also be combined with the application of mupirocin ointment, internal cephalosporin, penicillin antibiotics for anti-infection treatment. However, it should be noted that impregnated vesicular tinea pedis should not be used with strong exfoliative drugs such as podophyllotoxin, and attention should also be paid to wearing shoes and socks with strong breathability and washing feet diligently. When taking medication internally, liver and kidney function monitoring should be done to avoid side effects such as drug liver injury, and if the person is allergic to the relevant drugs, it is forbidden to use them. The impregnated vesicular tinea pedis, it is best to consult a doctor in a timely manner, follow the doctor’s instructions to use medication, do not unauthorized use of medication, so as not to delay the condition.