Cold thighs and calves may be related to kidney yang deficiency, spleen yang deficiency and other reasons, need to identify and treat, you can choose to take the Golden Chamber Kidney Qi Pills, with the seeds of Lizhong Pills and other drugs, please follow the doctor’s instructions for the specific use of medication. 1. Jin Gui Kidney Qi Pill: composed of dihuang, yam and cornelian cherry, it has the effect of warming and tonifying kidney yang (warming and replenishing kidney yang), transforming qi to move water (promoting the movement of gases, thus facilitating the movement of water and liquids), and is mainly used for treating kidney yang deficiency resulting in coldness and limb coldness (fear of coldness, coldness of the limbs), oedema, lumbar and knee soreness and tenderness (a feeling of soreness and weakness of the lumbar and knee), and dysuria (unruly urine), and so on. The adverse reactions and precautions of Jin Guo Ren Qi Wan are not clear. Contraindications: Pregnant women should not take it; avoid room desire and gas; avoid eating raw and cold food. 2. Radix Rehmanniae Pill: composed of Radix Rehmanniae, Radix et Rhizoma Ginseng, Rhizoma Atractylodis Macrocephalae, Radix et Rhizoma Glycyrrhizae, Glycyrrhiza Uralensis, it has the efficacy of warming the middle Jiao and strengthening the spleen, and it is suitable for the deficiency of spleen yang which leads to cold limbs, loose stools (loose feces that are thin and unshapely), and cold pain in the epigastrium (cold and painful sensation in stomach, epigastric and abdominal areas). Adverse reactions and contraindications are not clear. Note: Use with caution in pregnant women, etc. If you feel unwell and need to use the medicine, please go to the hospital and use the medicine under doctor’s supervision.