Clinically there is no female calf cold alert four diseases this statement, female calf cold is generally physiological reasons or pathological reasons (such as anemia, arterial occlusive vasculitis, Raynaud’s disease, hypothyroidism, etc.) caused. 1. Physiological reasons: Because the calves are far away from the heart, blood circulation is relatively slow, if women do not pay attention to keep their legs warm and prevent cold in the cold season of winter, the symptoms of cold calves may occur, which is a normal phenomenon. 2. Pathological causes (1) Anemia: The human body mainly relies on blood flow to maintain a constant body temperature. Anemia will lead to insufficient blood circulation, low blood red pigment value and lack of red blood cells, which will lead to cold calves in women. (2) Arterial occlusive vasculitis: mainly manifested as ischemia and hypoxia of the lower limbs caused by narrowing or occlusion of lower limb arteries, in the initial stage, it can be manifested as coldness of the calves, accompanied by numbness, and in severe cases, it will affect normal walking. (3) Raynaud’s disease: In the early stage of Raynaud’s disease, patients show mental tension, excitement, anxiety, fear, spasm of acromegaly, etc., which will lead to local ischemia, skin pallor, local cold and wet sensation, tingling and numbness of consciousness, as well as dyskinesia, and also the symptom of coldness of the calves. (4) Hypothyroidism: Patients with hypothyroidism usually have a decrease in thyroid hormone secretion, which leads to low metabolism and is usually manifested as cold limbs, so cold calves in women may be caused by hypothyroidism. It is recommended to consult a doctor in time to identify the cause of the disease, and follow the doctor’s instructions for targeted treatment.