Since the 1970s, traditional medical institutions have commonly used corticosteroids (referred to as hormones) to treat skin diseases. Topical ointments or creams synthesized with hormone preparations, such as dermaplanin, dermatologic king, dermatologic cream, de-inflammatory pine, paregoric pine, fluorine relaxation (skin relaxation), and lotion, are effective for a variety of skin diseases, such as contact dermatitis, UV allergy, itchy rash, neurodermatitis, and seborrheic dermatitis. In particular, it has a certain anti-itch effect on the itching caused by these skin diseases. Some people take hormones as a panacea for skin diseases, and when they have some discomfort (especially on the face), they choose to apply hormone-containing drugs topically. As a result, they induce complications that are troublesome. For some infectious skin diseases, topical application of such drugs is not only ineffective, but also reduces the local resistance and aggravates the condition. For a long time or a short time high dose of injection or internal dexamethasone, conning ketone, prednisone, cortisone, clobetasol and other corticosteroids, or the application of unknown truth contains hormones of the so-called secret formula treatment, the consequences are even more unimaginable. Long-term or large doses of topical corticosteroid drugs can lead to drug dependence, most commonly when the condition improves after using the drug, and once the drug is stopped, the primary lesion at the site of use is aggravated. When the hormone is reapplied, the above mentioned condition improves or disappears. If the drug is stopped again, the rebound reoccurs and is more serious than before. Patients who use hormones for a long time will have significantly thinner skin, dilated capillaries, and sometimes purpura, etc., especially on the face, which can appear as deeper persistent erythema. The longer the hormone is used, the more severe the rebound allergy is produced, and even susceptible to fungal infections and acne-like dermatitis. It may also cause mild hirsutism, excessive sweating, subcutaneous bleeding and wound healing difficulties. If treated with high doses of corticosteroids such as dexamethasone, Coninextrone, prednisone, etc. for a long time or for a short time, it can also cause complications such as obesity, hirsutism, acne, elevated blood sugar, hypertension, edema, decreased blood potassium, menstrual disorders, osteoporosis, aseptic osteonecrosis, and gastric and duodenal ulcers. It can also cause certain damage to the kidney, such as aggravating glomerular disease proteinuria, aggravating glomerulosclerosis, easily causing kidney calcification or stones, inducing or aggravating kidney infectious diseases, causing hypokalemic nephropathy, etc. It can also cause a series of substance metabolism disorders such as sugar, protein, fat and water electrolyte, etc., and damage the body’s defense system and inhibit immune response ability.