Another patient with simple congenital heart disease who lost the chance of surgery at such a young age, too bad, only 21 years old. A hole in the heart, such as atrial septal defect, ventricular septal defect, is a simple congenital heart disease, timely treatment, small risk, good results. But the delay to severe pulmonary hypertension, it is tricky, some will lose the opportunity to operate, can only take drugs to continue life, cheap drugs are not effective, and sildenafil, bosentan, andrisentan effect will be better, but is too expensive, the average family can not afford. Hypertension has been heard of, pulmonary hypertension, many people will be unfamiliar. If the structure of the heart is compared to a house, it can be simply summarized as “two rooms, two chambers and eight corridors”. The “atria” are the heart chambers, namely the left and right atria. The “chambers” are the ventricles, i.e., the left and right ventricles. The “eight corridors”: the superior and inferior vena cava are connected to the right atrium, the right ventricle sends the pulmonary artery to the lungs, the four upper left, lower left, upper right and lower right pulmonary veins are connected to the left atrium, and the left ventricle sends the aorta. There are four doors inside the house to control the unidirectional flow of blood: the two-lobe unidirectional door of the left atrium opening to the left ventricle is called mitral valve, the three-lobe unidirectional door of the right atrium opening to the right ventricle is called tricuspid valve, the three-lobe unidirectional door of the left ventricle opening to the aorta is called aortic valve, and the three-lobe unidirectional door of the right ventricle opening to the pulmonary artery is called pulmonary valve. The blood circulation flow of human body is from left ventricle – aorta – whole body – upper and lower vena cava – right atrium – right ventricle – pulmonary artery – lung – pulmonary vein – left atrium – left ventricle. Generally, blood pressure is measured with a cuff, and the pressure is measured in the brachial artery of the upper arm, which is connected to the aorta, and the aorta is connected to the arteries of the whole body, that is, the ordinary blood pressure is measured to know the pressure of the left ventricle to push the blood flowing to the whole body through the aorta and all levels of branch arteries. And for blood to flow to the lungs to expel carbon dioxide and absorb oxygen, it needs to be pushed by the right ventricle to send blood to the pulmonary artery and its branch-by-branch, which also generates a pressure. If the blood pressure in the pulmonary arteries is too high, this is also abnormal and we call it pulmonary hypertension. Pulmonary hypertension can be divided into five categories of causes, the most unfortunate of which is caused by congenital heart disease. In a normal heart, the left and right halves are separated from each other; between the left and right atria is the atrial septum, and between the left and right ventricles is the ventricular septum. In patients with atrial septal defect and ventricular septal defect, the left and right halves of the heart are connected. At first, the pressure on the left half of the heart is higher than the right half, so through this hole, blood flows from the left to the right. This can cause heart failure due to overloading of the heart on one hand, while on the other hand it can lead to excessive blood flow to the pulmonary artery. After a prolonged shock, the small pulmonary artery branches will spasm and then slowly occlude. This is like a blocked water pipe in front of you, and to ensure drainage, you have to increase the pressure. The right ventricle, which pushes blood into the pulmonary artery, becomes increasingly burdened, and the right ventricle slowly becomes overwhelmed. And the blood on the right side of the heart are the body absorbed oxygen, oxygen content is relatively low, so purple and black, the blood on the left side of the heart is the lungs absorbed oxygen, oxygen content is relatively high, so bright red. When the left side of the heart is mixed with the purple-black blood flowing from the right side and sent to the whole body, the lips and skin, which should show the color of bright red blood, will become purple-black, and the whole body will lack oxygen, causing all organs to work badly, and will be powerless and faint. Ultimately, the person will not be able to function because of heart or whole body failure. In severe pulmonary hypertension, it is not helpful to patch the hole in the heart because it is difficult to open the small pulmonary arteries once they are occluded. Simple congenital heart diseases, such as atrial septal defect and ventricular septal defect, are diseases that can be treated relatively easily, but if they are delayed until severe pulmonary hypertension, it will be too late to regret.