Many patients who come to the pain department and hear about “nerve block therapy” ask “is it a closed injection”, thinking that it is a “coping therapy” and can only temporarily relieve pain. In fact, this is a misunderstanding. The “closed” commonly known as “focal injection”, originated in the former Soviet Union, also known as procaine closed therapy, is the injection of procaine in the body’s local pain points, in order to play a temporary pain relief. “Focal injections are generally used in the treatment of trauma, strain and degenerative osteoarthrosis of muscles, ligaments, fascia, tendon sheaths, bursae and bony fiber ducts. Besides procaine, lidocaine, prednisolone, dexamethasone, etc. are commonly used, with simple operation and few complications. Since the “closed” injection solution contains prednisolone, dexamethasone and other hormone ingredients, some doctors are not familiar with the pharmacological knowledge of hormones, unreasonable selection of cases, unreasonable dose and dosing time and long-term application of large amounts of hormones caused by “bone fragility “Some doctors are familiar with the pharmacological knowledge of hormones, so they do not select cases and arrange the dose and time of administration of hormones reasonably. It is estimated that this is the main reason for people’s panic about “closed”. Nerve block therapy is currently the most basic means of pain treatment; international common definition: refers to the injection of drugs into the spinal ganglion, plexus or nerve, sympathetic ganglion, etc., or physical, chemical methods, or needle puncture in the nerve, blocking nerve conduction function. Chemical nerve blocks are mostly performed with low concentrations of local anesthetics, but also with high concentrations of local anesthetics, ethanol, phenol, and other nerve-destroying drugs to achieve long-term analgesia. Physical nerve blocks are commonly used in thermal coagulation therapy, cryotherapy, and also nerve block treatment with mechanical injury methods. Nerve block techniques are difficult, complex and require precision, and are used clinically not only for analgesic treatment, but also for diagnosis, prognosis and disease prevention. Since nerve blocks are applied directly to the nerves, some nerves are located deeper and surrounded by more important blood vessels and organs if not done properly can cause more serious complications. Therefore, nerve block treatment cannot be done by anyone and must be performed by a physician with formal training and clinical experience. Thus, “closure” and “nerve block” are two very different treatment methods, so do not consider the nerve block currently used in our pain department as simply “closure”; of course In addition to the safe and effective use of nerve blocks, the pain department also has a variety of treatments to relieve the pain of patients.