HFMD is already contagious during the incubation period and thereafter from the onset of the disease to about 2 weeks. Hand, foot and mouth disease is a highly contagious infectious disease, mainly caused by the enterovirus coxsackievirus, manifested as red herpes of varying sizes on the hands, feet, mouth and buttocks, with a variety of lesion patterns, and some intraoral lesions can cause ulcerative lesions. The disease has an incubation period of 2-10 days, when the child is already infectious and needs to be promptly identified and treated in isolation. Within 1-2 weeks of the disease process, the patient will have symptoms such as herpes on the hands, feet, mouth and buttocks, fever, irritability, fatigue and loss of appetite. At this time, the disease is extremely contagious and treatment measures should be actively taken to relieve the symptoms of the affected child. It is recommended that children with HFMD should be disposed of separately from their secretions, feces, clothing and household items to avoid cross-infection.