Hand, foot and mouth disease is an enteroviral infection, which is contagious and has a natural course of 7-10 days, with the most prominent symptoms in severe cases on days 2-5 of the disease course. The main symptom of typical HFMD is oral herpes on hands and feet, which can be accompanied by fever and gastrointestinal symptoms. Treatment is mainly symptomatic, and symptoms can gradually recover in about 1 week. Children with severe cases need to be promptly seen in the pediatric department of a hospital and treated in isolation to interrupt further development of the disease. Since the disease is contagious, the secretions, feces, clothing and household items of the affected children should be handled separately to avoid spreading the disease and causing cross-infection. For children with mild disease, parents should pay attention to the development of symptoms, eat a light diet, drink more water, work and rest regularly, and get enough sleep to improve the body’s resistance.