Is there a relationship between pancreatitis and pancreatic cancer and can pancreatitis cause pancreatic cancer? As we all know, pancreatitis is divided into acute pancreatitis and chronic pancreatitis. Acute pancreatitis is often caused by bile reflux, alcohol injury, hyperlipidemia and other causes of pancreatic injury, which induces severe abdominal pain, abdominal distension, jaundice, and even clinical manifestations such as shock and organ dysfunction. Chronic pancreatitis is mostly caused by multiple causes of segmental or diffuse progressive inflammation and fibrous lesions of the pancreatic parenchyma, resulting in pancreatic duct stenosis, pancreatic stone formation, pancreatic calcification and other manifestations, which can eventually lead to pancreatic hypersecretion. The exact cause of pancreatic cancer has not been determined yet, but a lot of statistics show that patients with pancreatic cancer often have a high protein and high fat diet, long-term smoking and alcoholism. Patients with long-term exposure to certain metals, asbestos, N-nitrosomethane, β-naphtholamine, and patients with diabetes are significantly more likely to develop pancreatic cancer than the general population. In addition, the relatives of pancreatic cancer patients have a significantly higher risk of developing pancreatic cancer, which suggests that pancreatic cancer is closely related to genetic factors. It can be seen that both acute pancreatitis and chronic pancreatitis can lead to pancreatic parenchymal damage, and pancreatic parenchymal damage is indeed a high risk factor for pancreatic cancer, but it is not comprehensive and objective to blindly assert that pancreatitis can lead to pancreatic cancer.