Diabetic foot and leg pain may be related to diabetic peripheral neuropathy, vasculopathy, it is recommended that early examination to clarify the cause of the disease, you can take medications to lower blood sugar, vasodilator drugs, nutritive nerve drugs under the guidance of the doctor. 1. Hypoglycemic drugs: common ones are metformin (metformin): mainly inhibit hepatic glucose output, α-glucosidase inhibitor (acarbose, voglibose): slow down the absorption of carbohydrates, sodium-glucose cotransporter protein 2 inhibitor (engegliflozin, dagliflozin): promote the renal excretion of glucose. 2. Vasodilator drugs (bepridin sodium): activate adenylate cyclase, inhibit the influx of Ca2+ and the generation of thromboxane A2, etc., thus having antiplatelet and vasodilator effects. 3. Nutritional nerve drugs (Epalrestat): can improve axonal flow abnormalities, increase the density of myelinated nerve fibers in the sciatic nerve, thickness of peroneal nerve myelin sheath axonal area, axonal cylindrical rate, and thus nutritional nerve. The above suggestions are for reference only, if diabetic patients with diabetic foot pain and leg pain, please standardize the use of drugs under the guidance of a doctor, do not take medication without authorization, so as to avoid adverse consequences.