Diabetic patients with cerebral infarction walking calf thigh muscle swelling and pain need to clarify the cause of the disease, may be diabetes combined with lower limb vasculopathy, diabetic peripheral neuropathy and other factors, need to be under the guidance of the doctor to carry out targeted treatment, such as drug therapy, interventional therapy, etc., such as lower limb vasculopathy can be used to improve the atherosclerosis of the atherosclerosis of the lower limb atorvastatin. 1. Diabetes mellitus combined with lower limb vasculopathy: long-term poor blood sugar control will lead to lower limb arterial vasculopathy, causing vascular stenosis, occlusion, etc. leading to pain; should actively control blood sugar, accompanied by atherosclerosis can be used in atorvastatin treatment, severe occlusion can also be treated by surgical intervention. 2. Diabetic peripheral neuropathy: abnormal sensation of thighs and calves, such as numbness and pain, etc.; in addition to active control of blood glucose, anti-oxidative stress treatment with lipoic acid, improvement of microcirculation by pancreatic kininogenase, and nutritive neurological treatment with methylcobalamin can also be used. Diabetic cerebral infarction patients appear walking calf thigh muscle swelling and pain due to many reasons, it is recommended to go to the hospital, ask the doctor to make a judgment, to clarify the cause of the disease and treatment.