The average incubation period of AIDS is 10 years, that is, the shortest AIDS can be 2-3 years after the onset, and the longest can have reached more than ten years after the onset. During the incubation period, HIV-infected patients do not have obvious symptoms and their quality of life is not affected. Once the disease develops, it can be manifested as various clinical manifestations during the onset of the disease. Generally, the initial symptoms are like a cold, such as general fatigue and weakness, loss of appetite and fever. With the aggravation of the disease, there can be invasion of various organs, persistent fever of unknown origin, which can last for 3-4 months, cough, shortness of breath, dyspnea, diarrhea, blood in stool, enlargement of liver and spleen, etc.