Hemorrhoids, as a common unspeakable, some people are familiar with, some strange, but most of them have some vague impression, it is inevitable that a few relatives and friends around have suffered from this kind of disease, especially in Sichuan. Famous ancient literature “Zhuangzi? Lie Mikou” has this record: “The King of Qin has a sick call doctor, broken carbuncle ulcer seat of the car a ride; lick hemorrhoids of the car five times. The more healed, the more cars.” The king of Qin in a high position, for the pain of hemorrhoidal disease shed five horse-drawn carriage to reward the doctor, the modern equivalent of a luxury car, coupled with the reward of war heroes with the same honor. At present, modern medicine on the pathogenesis of hemorrhoidal disease is still diverse, the interpretation of the doctrine of more than 10 kinds of mainly include: varicose veins doctrine, vascular hyperplasia doctrine, arterial distribution doctrine, hemorrhoidal hernia formation doctrine, the anal cushion under the transfer of doctrine, bacterial infection, anal canal stenosis doctrine, pressure gradient doctrine and so on. Each theory from a certain aspect of the interpretation of the causes of hemorrhoids, as if the blind man feeling the elephant, the elephant is like a dustpan or like a pipe, or like a wall? Only for one side of the explanation is often not comprehensive, there is a leakage of suspicion, can not be a complete interpretation of hemorrhoidal disease development and evolution of the law. Chengdu Anus Intestinal Specialized Hospital Professor Yang Xiangdong that the occurrence and development of hemorrhoidal disease mechanism in line with the principle of biological degeneration, accordingly proposed hemorrhoidal pathogenesis of degeneration theory. The core concept of the doctrine is: hemorrhoidal disease is actually the end of the rectal tissue degenerative changes, that is, aging degeneration. With age, the function of the body gradually decline, hemorrhoidal disease is physiologically inevitable, is the internal cause, is the root. Diet spicy, external six obscene, internal injury seven feelings are secondary factors, is the external cause, is subordinate. Objectively speaking, since human beings walk upright, they can no longer get rid of the entanglement of anal and intestinal diseases. The degeneration of hemorrhoids, mainly including the following two aspects: 1. The degeneration of blood vessels: the end of the rectum arterial vascular relatively rich and stable, but in contrast, the end of the rectum veins of smooth muscle and elastic tissues are less, connective tissue components are more. Based on such histo-anatomical differences, the venous return vessels gradually become loose in the course of life due to various reasons (e.g., recurrent inflammation, tissue decline and aging, etc.), and their function is bound to be reduced. The arterial supply of the end of the rectum gradually exceeds the proportion of venous return, leading to the continuous pooling of venous blood, and ultimately the formation of a tortuous, dilated venous mass at the lower end of the rectum, which gives rise to hemorrhoidal disease. 2. tissue degeneration: with the growth of age and a variety of external causes, such as increased abdominal pressure, squatting force defecation, etc., part of the rectal muscle, connective tissue, mucosa degeneration, fracture, tearing and the formation of the movement from the top to the bottom of this degenerative changes, not only limited to the end of the rectum, but the rectum from the top to the bottom of a whole change, the manifestation of the entire rectal mucous membrane and the submucosal tissues and the separation of muscle layer, that is, rectal mucosa in the removal. That is, the rectal mucosa is detached internally. This degenerative change is irreversible and continuous. Prof. Shi Zhaoqi, founder of the Anal and Intestinal Branch of the Chinese Society of Traditional Chinese Medicine (CSTCM), has proposed the “four-step injection method of eliminating hemorrhoids”, which has not only won numerous awards, but is also widely acclaimed both at home and abroad. The four-step injection levels are: (1) upper rectal artery branches; (2) submucosal layer; (3) mucosal lamina propria; (4) sinusoidal vein lower pole. The levels of the four-step injection can be simply summarized as “superior, inferior, deep and superficial”. The “upper and lower” levels of injection of anti-hemorrhoidal spirit can play a good role in closing the blood vessels and cut off the flow. The two steps of “deep and shallow” are injected consecutively, and their main purpose is to make the degenerated rectal mucous membrane layer and some of its muscle tissues adhere and fix and reset, that is, to play the role of suspension. Over the decades, the four-step injection therapy has been utilized in a huge amount of clinical practice at home and abroad, with considerable achievements, and all of which undoubtedly confirms the rationality of the degeneration theory. Why do hemorrhoids require four-step injections, each targeting degenerating blood vessels and degenerating tissues? It is the inevitable characteristics of human tissue degeneration that determine the success of the four-step injection method. The original theoretical basis of PPH (circumferential hemorrhoidal mucosal anastomosis) is the doctrine of anal cushion subluxation. Under the guidance of this doctrine, PPH has been rapidly popularized and applied worldwide. Chengdu Anorectal Specialized Hospital has carried out this technology since 2001. According to the theory of anal cushion displacement theory, using PPH this technology, theoretically should make the treatment of hemorrhoids has been a fundamental “solution”, but clinical practice has found that PPH in fact can not be realized hemorrhoids complete “cure”. In the lower rectal tissue after the implementation of large-capacity circumcision, hemorrhoidal disease actually recurred, and even the proportion is not small, such as Gao Xianhua [3] and others through the English literature Meta-analysis showed that the recurrence rate of PPH is higher than that of traditional hemorrhoidectomy (CH) [17 studies, 636 cases in the PPH group, 625 cases in the CH group, OR 2.96, 95% CI (1.57, 5.56); P=0.0008). 0.0008). If we analyze according to the principle of regression theory, PPH technique is actually unable to “cure” hemorrhoidal disease, and the recurrence is irreversible. In recent years, this problem has attracted the attention of some clinical experts and device development engineers at home and abroad. Happily, the national enterprise Suzhou Tianchen International Medical Technology Co., Ltd. in a very short period of time has developed and launched a special device – TST Starr + (Tissue-Selecting Therapy stapler and Starr fusion of more optimized operation), and by Ren Donglin, He Ping, Autonio, Longo, Gabriele and others. It has been tried and tested by more than 10 senior anorectal specialists at home and abroad, such as Donglin Ren, Ping He, Autonio Longo, Gabriele Naldini, etc., and has achieved very good clinical results. This technique greatly increases the amount of tissue cut mainly from the rectal mucosa. Theoretically analyzed from the doctrine of regression, it will certainly greatly improve the long-term cure rate of hemorrhoidal disease and reduce the recurrence rate compared with the traditional PPH technique. Certainly need more clinical practice observation from more research centers to find the regularity of its application. Undoubtedly, Hemorrhoidal Degenerative Disease is based on the insights of doctors’ clinical practice, and what we all expect is just to provide more comfortable and perfect treatment for the majority of patients in the study of the occurrence, development and evolution mechanism of hemorrhoidal disease, which is a disease that widely jeopardizes the health of human beings.