When you look at a patient’s abdominal ultrasound report or physical examination report in the clinic, you can often see the diagnosis of fatty liver written on the diagnosis, and some patients often infer that they have hyperlipidemia, is this true? Is it true? What exactly is the connection between hyperlipidemia and fatty liver? Does having a fatty liver mean having hyperlipidemia? Fatty liver is a clinicopathological syndrome in which the main body of the lesion is in the lobules of the liver and diffuse steatosis of the hepatocytes is the main cause. The liver is the main site of lipid synthesis and metabolism, and excessive accumulation of lipids in the liver leads to a fatty liver. One study found that patients with hyperlipidemia accounted for more than half of all patients with fatty liver, indicating that the development of fatty liver is closely related to the level of blood lipids. In addition, related studies have found that patients with hypertriglycerides account for the majority of patients with fatty liver, while patients with simple hypercholesterolemia account for only a small percentage. In normal individuals, the amount of fat in the liver is 5% of the liver weight, while in patients with fatty liver it can be 40% to 50%, mainly triglycerides and fatty acids, with only a small increase in phospholipids, cholesterol and cholesteryl esters. Therefore, hyperlipidemia, as an important factor leading to fatty liver, can promote the occurrence and development of fatty liver, and is mainly associated with high triglycerides. The detection rate of fatty liver was significantly higher in the hyperlipidemic group compared to the normolipidemic group. This may have several reasons: 1, because of the long-term consumption of high fat, high cholesterol and other high-calorie foods, and the body can not effectively consume the heat, triglycerides in the liver intake and synthesis of the liver increased, more than the liver’s lipidation and oxidation capacity, excessive fat deposition in the liver, the formation of fatty liver; 2, hypertriglyceridemia caused by insulin resistance, as well as obese people at the same time the existence of Insulin resistance, resulting in disorders of lipid metabolism, excessive fat infiltration in the liver, fat particles invade the hepatocytes, making the hepatocytes swollen, compressing the liver blood sinusoid, gradually causing ischemia, degeneration, necrosis, the formation of fatty liver. 3, fatty degeneration of hepatocytes and free fatty acid damage to hepatocytes, affecting the oxidative metabolism and energy conversion of hepatocytes, resulting in damage to hepatocytes, with the destruction of hepatocytes, their metabolic function is affected, aggravating the disorder of lipid metabolism in the body, forming a vicious circle, promoting the occurrence of fatty liver. Therefore, abdominal ultrasound indicates fatty liver does not necessarily indicate hyperlipidemia, and the two are closely related but not absolutely equivalent. But whether it is fatty liver or hyperlipidemia, you need to start changing your poor lifestyle, and if your liver function index is not good, you may also need to use medication, so pay attention to lipids and fatty liver!