In the case that fatty liver is detected after chemotherapy for lung adenocarcinoma, patients need to follow the doctor’s instruction for general measures, drug treatment and so on. Patients with lung adenocarcinoma combined with fatty liver firstly need to clarify the causes of the disease, and clarify the causes of the disease, such as drinking alcohol, long-term intake of high-fat diet, obesity, lack of exercise, diabetes, hepatitis, acute or chronic liver damage caused by certain drugs, and so on. Specific measures are as follows: 1. General measures: Usually, patients with mild fatty liver disease need to actively regulate their diet, control calorie intake and develop good dietary habits (high protein, high vitamin, low sugar, low fat diet). Patients also need to take appropriate physical exercise and avoid sedentary lifestyle. Avoid drugs that may be hepatotoxic and limit alcohol consumption. 2. Causal treatment: If the cause of the disease is clear, the patient needs to actively treat the original disease. 3. Drug treatment: Usually, for adults with body mass index (BMI) greater than or equal to 30 kg/m², and patients with BMI greater than or equal to 27 kg/m² and accompanied by hypertension, type 2 diabetes, and dyslipidemia, relevant drugs can be used according to doctor’s instruction. It is recommended that when fatty liver is detected after three times of chemotherapy for lung adenocarcinoma, reasonable treatment should be carried out according to the degree of the disease and in accordance with the doctor’s prescription.