Examination and diagnosis of cyanosis of extremities Symptom presentation: cyanosis of extremities, onset characterized by cold sensation and cyanosis of extremities. It is mostly seen in young women. Diagnosis of symptoms: The lesion often involves both hands and manifests itself at the ends of the extremities. Persistent, uniform cyanosis may appear throughout the hands and wrists or even the back, cold, and exposure to cold air may aggravate the symptoms, but warm environments often fail to reduce or eliminate them, with swollen fingers, a feeling of stiffness, and sweaty palms. No ulcer or gangrene formation was seen. Differentiation: 1. Cyanosis is limited to peripheral cyanosis at the end of the limbs, the ear chakras, the tip of the nose and other parts of the body with low body temperature, which can be improved by keeping warm. 2, infants and children with generalized cyanosis accompanied by inspiratory difficulties should be considered to have amniotic fluid aspiration, milk or vomit choked into, and immediately suck it out with a suction tube and give oxygen. Antibiotic therapy should be given if pneumonia is suspected. Immature children with generalized cyanosis and suspected pulmonary atelectasis and whistling distress syndrome should be given positive pressure oxygen and further clarify the diagnosis. 4. For those with generalized cyanosis and positive cardiac signs, congenital heart malformation, diaphragmatic hernia or tracheoesophageal fistula should be further excluded, and joint diagnosis and treatment with relevant departments should be provided. The former is due to the increase of reduced hemoglobin in the blood or contains abnormal hemoglobin. The latter is due to abnormal pigmentation of the skin model membrane (such as silver hyperpigmentation, gold hyperpigmentation, Addison’s disease, etc.) or silver or gold hyperpigmentation due to foreign body deposition. It is generally limited to the skin.