Therapeutic drugs for small intestinal bacterial overgrowth include Lactobacillus plantarum, Lactobacillus acidophilus, Lactobacillus casei and so on. 1. Lactobacillus plantarum: Lactobacillus plantarum can produce organic acid, bacteriocins and other kinds of antibacterial substances, so as to improve the overgrowth of intestinal microflora and enhance the body’s immunity. Adverse reactions and contraindications are not clear. 2. Lactobacillus acidophilus: Lactobacillus acidophilus can effectively inhibit the growth of bacteria in the intestinal tract, form a protective film to protect the stomach and intestines, produce a variety of vitamins, and adjust the intestinal flora. Adverse reactions and contraindications are not clear. 3. Lactobacillus casei: Lactobacillus casei can accelerate the removal of bacteria in the intestinal tract, treat the bacterial overgrowth in the small intestine, regulate the intestinal flora disorders, and enhance immunity. Adverse reactions and contraindications are not clear. If the patient has small intestinal bacterial overgrowth, it is recommended to go to the hospital in time for standardized treatment. All of the above drugs should be applied under the guidance of a physician, and should not be used without authorization.