Calf swelling after infusion in pregnant women is generally not related to infusion, and it is considered to be related to abnormal water metabolism in pregnant women, and hypertensive disorders in pregnancy, hypoproteinemia, thrombophlebitis, or renal-related diseases cannot be ruled out. If a pregnant woman has swollen legs after infusion, she should go to the hospital in time for further examination, such as checking blood and urine routine, blood biochemistry, lipid analysis, D-dimer measurement, ultrasound examination, including lower extremity venous ultrasound, prenatal examination and other related examinations, and if necessary, please ask for a consultation with the relevant departments to assist in the diagnosis and treatment, and then decide on a further treatment plan according to the results of the examination. There are many reasons for leg swelling during pregnancy. If you experience leg swelling, it is recommended that you go to the hospital in time for examination and follow the doctor’s instructions for active treatment after clarifying the cause of the disease.