First, the contraindications of pairing “Ben Jing・Preceding Regulations” pointed out that: “Do not use the opposite, the opposite of each other.” However, the consequences of the opposite and the opposite are not the same. The pairing can make some aspects of the efficacy of the drug weakened, but is a relationship that can be utilized in the pairing, not an absolute contraindication. And “the opposite for harm, even more than the opposite of evil”, may jeopardize the patient’s health, and even life-threatening. Therefore, the opposite of the drug is prohibited in principle. At present, the medical profession commonly recognized contraindications, there are “eighteen anti-” and “nineteen fear. Eighteen against: licorice against glycyrrhiza glabra, Morinda citrifolia, seaweed, coriander; aconite against shellfish, melon basket, half-summer, Ampelopsis japonica, Bletilla hyacinthina; quinoa against ginseng, Salvia miltiorrhiza, Salvia miltiorrhiza, XuanShen, Bitter ginseng, Hosaneum, Paeonia lactiflora. Nineteen fears: Sulfur yellow fear Park nitrogen, mercury fear Arsenic, wolfsbane fear Mithrax, Croton fear Petunia, Clove fear Tulip, Chuanwu, Caowu fear Rhinoceros horn, Toothbrush fear Sanleng, Guan Gui fear Shi Lipstick, Ginseng fear Wuling Lipstick. Five generations after Shu Han Baosheng revised “Shu Materia Medica”, the first statistical number of seven feelings, mentioned “phase of sixty kinds, the opposite of eighteen kinds”, today’s so-called “eighteen against the” name, cover from this. Phase fear is one of the seven feelings of traditional Chinese medicine, the content has been as mentioned. But from the Song Dynasty, some medical writings, fear, evil, anti-name use of confusion, and the “Classic” “fear” of the original meaning is contrary. The “nineteen fears” as a contraindication to compounding was put forward in this situation. For the eighteen anti, nineteen fear as a contraindication, although the successive generations of medical scientists to comply with the letter of the majority, but there are different views, some people believe that the eighteen anti, nineteen fear is not an absolute contraindication; some medical scientists also believe that the opposite medicine with, can be contrary to each other, resulting in a strong efficacy. Still if properly utilized, can cure the disease. In modern times, eighteen against, nineteen fear of pharmacological experimental research, has made a lot of achievements. However, due to the fact that there are many problems involved in the study of 18 antiseptic and 19 dicamba, the experimental conditions and methods vary from place to place, which makes the results of the experiments differ greatly. Most of the simple toxicity tests yielded negative or contradictory results. The results of early studies tended to be totally rejected; in recent years, the observation has been gradually deepened, and the call for “not to be easily rejected” has been raised. In addition, there are experiments to prove that the eighteen anti, nineteen fear of the size of the toxic side effects of drugs on the human body, and the absolute dose of drugs and the relative dose of each other. Generally speaking, due to the experimental research on the eighteen anti, nineteen dicamba is still in the early stage, it is still too early to decide on its trade-offs, pending further in-depth research. Therefore, if there is no sufficient evidence and experience in the application of the medicines of 18 against 19 dicamba, they should not be used in general. Second, pregnancy contraindications pregnancy contraindications, mainly to discuss pregnancy contraindications. Pregnancy contraindication refers to women’s pregnancy in addition to the interruption of pregnancy, induction of labor, the use of drugs is contraindicated. Ancient medicine early on pregnancy contraindications have knowledge, the Eastern Han Dynasty “Shen Nong Ben Cao Jing” that contains six kinds of abortifacient drugs, the Liang Dynasty “Materia Medica Collection Note, preface examples of general medicine,” dedicated to abortifacient drugs, containing 41 kinds of abortifacient drugs. From a historical point of view, in ancient China, abortion was against the traditional moral concepts of China. Therefore, the previous record of abortifacients, mainly from the perspective of pregnancy contraindications to recognize, treat, rather than seeking effective abortifacients. In the many contraindications to pregnancy, different drugs on the degree of harm to pregnancy is different, and therefore should be treated differently in clinical practice. Ancient contraindications to pregnancy mainly mentioned prohibited and contraindicated, rarely mentioned the use of caution. In recent times, according to clinical practice, the contraindication of pregnancy drugs are divided into two categories: prohibited and cautious use. The prohibited drugs are mostly highly toxic drugs, or drugs with severe effects, and drugs with strong abortifacient effects. The drugs to be used with caution are mainly drugs for promoting blood circulation and removing blood stasis, drugs for promoting qi, drugs for attacking the lower part of the body, and drugs for warming the inner part of the body. Prohibited drugs: Mercury, arsenic, andrographis paniculata, powdered powder, spotted fibers, strychnine, toadstools, Chuanwu, Caowu, veratrum, cholagogues, guaties, croton, glycyrrhiza glabra, halibut, coriander, marionette, merchant’s land, musk, dried lacquer, leeches, gadflies, trigonelline, curcuminoid, and so on. Cautious medicines: hyssop, chuanxiong, safflower, peach kernel, turmeric, mudanpi, citrus aurantium dulcis, citrus aurantium dulcis, rhubarb, senna, aloe vera, mangosteen, epiphyllum, cinnamon, and so on. Among the many contraindications to pregnancy, the reasons for contraindications to pregnancy are varied, of which the ability to cause abortion is the main reason for early contraindications to pregnancy. With the gradual deepening of the understanding of pregnancy contraindication drugs, the understanding of the reasons for pregnancy contraindication has also gradually deepened. Summarized, they mainly include: ① unfavorable to the mother, ② unfavorable to the fetus, ③ unfavorable to the course of labor; ④ unfavorable to the pediatrics. Today, whether from the point of view of drug safety, or from the point of view of eugenics to recognize these points, should be given great importance. In general, for pregnancy contraindication, if there is no special need, should try to avoid the use of the accident. If the pregnant woman must be used, should pay attention to the identification of accurate, master the dose and course of treatment, and through the appropriate concoction and compounding, minimize the harm of the drug on the pregnancy, so that the drug is effective and safe. Third, the dietary contraindications when taking medication dietary contraindications refers to the period of taking medication on certain food taboos, also referred to as food taboos, that is, usually referred to as taboos. Generally speaking, should avoid eating cold, hot, greasy, fishy, stimulating food, in addition, according to the different conditions, dietary taboos are also different. Such as hot disease should avoid eating spicy, greasy, fried food; cold disease should avoid eating cold, chest paralysis patients should avoid eating fatty meat, fat, animal offal and smoke, alcohol; liver yang hyperactivity, dizziness, irritability should avoid eating pepper, chili pepper, garlic, white wine and other hot and spicy products, spleen and stomach weakness should avoid eating deep-fried sticky, cold, hard, hard, indigestible food, sores, skin disease patients, should avoid eating fish, shrimp, crab Fish, shrimp, crab and other fishy and spicy stimulating food.