In order to minimize the discomfort caused by adverse reactions after vaccination, it is recommended not to receive MMR and B vaccine at the same time. The MMR vaccine is a combined live attenuated vaccine, which has more active ingredients and can prevent three diseases after vaccination, namely measles, mumps and rubella. Encephalitis B vaccine is divided into live attenuated and inactivated vaccines, which can prevent encephalitis B virus infection after vaccination. Since both vaccines may produce adverse reactions after vaccination, such as localized pain, mental disequilibrium, mild fever, etc., the incidence of such adverse reactions will be greatly increased when both are injected at the same time, which in turn will cause a strong sense of discomfort in the organism. To summarize, simultaneous vaccination with MMR and BSE vaccine is not recommended.