Pineal tumor refers to the increased secretion of gonadotropins and sex hormones caused by pineal tumor (the secretion of pineal gland is antagonistic to the pituitary gland), also known as precocious puberty syndrome and precocious giant genitalia syndrome. Common tumors include: adult pineal cell tumor, pineal cell tumor, glioblastoma, teratoma, germ cell tumor, seminomatous cell tumor, astrocytoma, etc. They account for about 1% of intracranial tumors and are mostly seen in boys. There are two main types of pineal cells: pineal parenchymal cells and glial cells. The most common pineal tumors are germ cell tumors and teratomas. 75% to 80% of pineal tumors are malignant, including germ cell tumors, adult pineal cell tumors and certain gliomas, and the rest are benign tumors, such as pineal cell tumors, teratomas, and dermatomal cysts. Pineal area tumor first radiotherapy (including gamma knife), surgery? 1.Some data reported: germ cell tumor in pineal region only accounts for 31%~36.5% of all tumors: preoperative MR, serum and cerebrospinal fluid specimens are examined for germ cell tumor related markers, clinically used are AFP, β-hCG and CEA, etc.; stereotactic biopsy. 2.Preoperative diagnosis of germ cell tumor other than pineal tumor, after excluding contraindications to surgery, direct surgery is not a good choice.