Nasal cancer is a malignant tumor that occurs in the top and side walls of the nasal cavity. It is one of the highly prevalent malignant tumors in China, and the incidence rate is the first among otorhinolaryngological malignant tumors. The symptoms are nasal congestion, blood in the snot, stuffy and blocked feeling in the ear, hearing loss, diplopia and headache. Most nasal cancers are moderately sensitive to radiation therapy, and radiation therapy is the first choice of treatment for nasal cancer. However, for more highly differentiated cancers, late stage of disease and recurrence after radiotherapy, surgical resection and chemotherapy are also indispensable means. Whether nasal cancer can be cured or not depends on the patient’s physical and mental quality, specific condition and timely treatment and other factors. 1. Physical and mental quality The stronger the physical quality of the patient and the better the state of mind, the faster the recovery in treatment and the greater the chance of cure. On the contrary, patients who are physically weaker and have a negative attitude will not only recover more slowly, but also have a high risk of affecting the treatment effect. With the rapid development of doctors’ level, as long as early stage nasal cancer patients can achieve early detection, early diagnosis and early treatment, they can achieve the goal of cure. However, when nasal cancer develops to middle or late stage, it is difficult to achieve the purpose of cure, because the cancer cells in middle or late stage have spread and metastasized, which increases the difficulty of treatment. 3.Whether timely treatment As mentioned above, early stage nasal cancer patients can be cured, but if they fail to go to the hospital in time, they may miss the best time for treatment, resulting in the delay of the disease and reducing the chance of cure. 4.Whether the treatment method is appropriate Many early stage nasal cancer patients may mistakenly think that their nasopharynx has been cured after surgery, and no longer insist on postoperative consolidation treatment (radiation therapy, biological therapy) and regular review in hospital. This will easily cause the cancer cells to resurface in the patient’s body after some time and recurrence will occur. Therefore, it is recommended that patients with early stage nasal cancer should insist on post-operative consolidation therapy after surgery, so that cancer cells in the body can be eliminated and there is no possibility of recurrence. Clinical manifestations 1. Primary cancer (1) Snotty blood and nasal bleeding If the lesion is located in the posterior wall of nasopharynx, when the nasal cavity or nasopharyngeal secretion is sucked backward, it may cause snotty blood (i.e. blood in the sputum when sucking backward) in mild cases and nasal bleeding in severe cases. This symptom is common in tumor with ulcerated surface or cauliflower type, but snotty blood is rare in submucosal type. (2) Ear symptoms: If the tumor is in the pharyngeal fossa or the round occipital area of the eustachian tube, due to the infiltration of the tumor, the tumor will compress the pharyngeal orifice of the eustachian tube, and the symptoms and signs of secretory otitis media will appear: tinnitus, hearing loss, etc. Clinically, many patients with nasal cancer are found because of ear symptoms. (3) Nasal symptoms primary cancer infiltrating into the posterior nostril area can cause mechanical blockage, and tumors located in the anterior wall of nasopharynx are more likely to cause nasal congestion. Nasal congestion accounts for 15.9% of the initial symptoms and 48.0% at the time of diagnosis. (4) Headache is a common symptom. Most of the clinical symptoms are unilateral persistent pain, mostly in temporal and parietal areas. (5) Eye symptoms Although nasal cancer invades the orbit or the nerves related to the eye, some patients still seek medical consultation with this symptom. Nasal cancer invasion of the eye often causes the following symptoms and signs: visual impairment (may be blind), visual field loss, diplopia, protrusion and limitation of eye movement, and nerve paralysis keratitis. Optic nerve atrophy and edema can be seen on fundus examination. (6) In the process of infiltration of nasal nerve, trigeminal nerve, abducens nerve, linguopharyngeal nerve and hypoglossal nerve are more involved, while olfactory nerve, facial nerve and auditory nerve are rarely involved. (7) Cervical lymph node metastasis is painless, hard, movable in the early stage, and fixed by adhesion to skin or deep tissue in the late stage. (8) Distant metastasis is the main complaint in individual cases. (9) Cachexia may die due to systemic organ failure, and there are also cases of sudden haemorrhage and death. 2.Nasal cancer combined with dermatomyositis Dermatomyositis is a serious connective tissue disease. The relationship between malignancy and dermatomyositis is not yet clear, but the incidence of malignancy in patients with dermatomyositis is at least five times higher than normal. Therefore, patients with dermatomyositis should undergo a careful whole body examination in order to detect hidden malignant tumors. 3.Hidden nasal carcinoma Enlarged lymph nodes in the neck are confirmed to be metastatic carcinoma by pathological section, but the primary carcinoma foci are not detected by multiple examinations or biopsies of the suspected areas, which is called hidden carcinoma of the head and neck (those with primary foci in the chest, abdomen or pelvis are not included in this category).