Postmenopausal vaginal bleeding is not a diagnosis of a disease, but a symptom. The most important thing is to find out the cause of this symptom so that it can be treated accordingly. The causes of postmenopausal vaginal bleeding include: postmenopausal hormone replacement therapy, long-term oral estrogen-containing health products, tamoxifen treatment for breast cancer, senile vaginitis, endometritis, cervical inflammation, trauma, foreign bodies, submucosal fibroids, endometrial polyps, ovarian tumors, intrauterine device, endometrial cancer, cervical cancer, etc. In principle, malignant lesions should be excluded before treating them as benign diseases. In principle, malignant lesions must be excluded before they can be treated as benign diseases. For patients with postmenopausal vaginal bleeding, the most common diagnostic method is diagnostic curettage, where the scraped out endometrium is sent to pathology department for histological examination, because postmenopausal vaginal bleeding must be alert to the possibility of endometrial cancer, especially for patients with combined obesity, hypertension, diabetes mellitus, breast cancer or hormone replacement therapy with single estrogen. For postoperative pathology suggesting atypical endometrial hyperplasia or endometrial cancer, prompt treatment should be given accordingly. After removing the malignant disease, the patient will be treated appropriately according to the type of disease. For postmenopausal vaginal bleeding, the cause can be benign or malignant, and the cause should be sought, and attention should be paid to whether it is a danger sign of endometrial cancer.