Cirrhotic hyperplastic nodules are caused by degeneration or necrosis of hepatocytes due to various etiologies. If the etiology persists, the regenerated hepatocytes have difficulty in restoring the normal liver structure and form irregular nodules, which can be divided into large, small and mixed nodules. It needs to be given high attention because patients with cirrhosis are prone to develop liver cancer, so it is important to identify the cause of producing hyperplastic nodules. The liver has a high regenerative capacity and normal physiological functions can still be maintained with 80%-70% of the normal liver removed. About one year after the removal of normal liver lobes in humans, the remnant liver can be restored to the weight of the original liver.