Minor triple yang hepatitis B surface antigen turn negative, virus turn negative, a small part of the population is because the virus is completely eliminated, the body recovery state. Most of them are still due to the weakening of viral activity through treatment, can not detect the specific antigen status, may not be out of complete recovery. Hepatitis B minor triple positive status suggests that the hepatitis B virus activity is weakened, the overall condition is stable, the examination of hepatitis B surface antigen negative, there is a very small possibility that the virus is completely eliminated, the physical condition of the body is completely recovered. Clinically, there is a large part of the population belongs to the body immunity enhancement, hepatitis B virus in the body almost no replication, through the hepatitis B 5 test can not detect the antigen, the patient himself belongs to the hepatitis B carrier state, with the body immunity weakening, there may be a recurrence of hepatitis B. The specific situation needs to be combined with the hepatitis B virus DNA test, the patient’s condition is not stable. The specific situation needs to be combined with the quantitative measurement of hepatitis B virus DNA and liver function to make a comprehensive judgment, once the recurrence of hepatitis B disease, we need to consult a doctor in time for observation and standardized treatment under the guidance of clinicians.