The third dose of the New Crown vaccine usually does not affect the kidneys and can be administered with confidence. The New Crown vaccination may cause some adverse reactions in the vaccinated person. In a healthy vaccinated population, it usually does not cause kidney damage or effects on the kidneys. It is recommended that people with severe kidney disease, or in the middle of a kidney disease flare-up, should not receive the New Crown vaccine. Common adverse reactions after the third dose of New Crown Vaccine are mainly localized pain at the vaccination site and mild systemic symptoms, such as mild fever, body fatigue, drowsiness, and mental confusion. The above adverse reactions usually subside within a few days, and there are usually no renal adverse reactions. Therefore, for those who are eligible for vaccination, they can be assured that the vaccination will not usually affect the kidney.