Hysterectomy can affect women’s body and mind, therefore, women should decide carefully before hysterectomy, and after surgery they should adjust their mindset in time and be optimistic about life. 1, the impact on physiology: hysterectomy will not only destroy the dynamic balance of endocrine between the uterus and ovaries, but also make the phenomenon of ovarian function decline. The reduced ovarian function will cause the serum estrogen level to drop, which may cause menopausal symptoms to advance significantly, and the skin to become rough and dull, and may also show symptoms such as hot flashes, night sweats, weakness and irritability. 2.Impact on sex life: Many women will have reduced sexual function after hysterectomy, such as reduced libido and difficulty in orgasm. 3, the impact on the psychological: In addition, the psychological changes also affect the quality of life of women after surgery. Some patients due to excessive worry can seriously affect the harmony of conjugal and family life, and may even produce depression, anxiety and other mental symptoms. In conclusion, there will be certain after-effects after hysterectomy, so we must decide carefully before the operation and pay attention to adjusting the mentality after the operation.