Whether or not a large uterus is harmful depends on the nature. If it is not caused by pathological factors, such as a large uterus by birth or pregnancy, there is usually no obvious harm. If the uterus is large due to pathological factors, there may be some harm to the body. 1, physiological uterus large 1, congenital factors: some women are born with a large uterus, for fertility or other uterine function will not have much impact, often do not need special treatment; 2, acquired factors: pregnancy, after childbirth, after miscarriage, the uterus has increased, generally not much impact, do not need special treatment; 3, hormone levels: estrogen and progesterone too much, caused by physiological reasons, generally do not need special Treatment. Second, pathological uterus large due to women with ovarian dysfunction, chronic uterine insufficiency, chronic inflammation, pelvic stasis, myometrial vascular sclerosis, adenomyosis and fibroids and other diseases, resulting in a large uterus, often accompanied by menstruation and leucorrhea abnormalities, abnormal vaginal bleeding, vulvar pain and other symptoms. Enlargement of the uterus due to such diseases can affect the normal physiological function of the uterus and cause female infertility, pelvic inflammatory disease and uterine inflammation. In this case, endocrine or imaging examinations should be performed to actively find the cause and reduce the damage caused by the original disease through relevant treatment.