What is sperm malformation rate?

  In addition to normal sperm, there are abnormal sperm in each person’s semen, the so-called “deformed” sperm, and the proportion of these “deformed” sperm in all sperm is called the sperm “deformation rate”.  The normal human sperm is a long cell with an external shape like a tadpole, and the sperm is divided into five parts: head, neck, middle, main and end segments. Since it is difficult to see the end segment of the sperm under a light microscope, it can be assumed that the sperm consists of a head (and neck) and a tail (middle and main segments). The sperm head is roughly oval, and the acrosome area should account for 40% to 70% of the head; the mid-section is slender and regular, approximately equal to the length of the head; the residual cytoplasm should not exceed 1/3 of the head size; the main segment should be finer than the mid-section, about 45 μm long, and the tail should not show the sharp folded angle of the broken flagellum. Sperm “malformation” refers to the morphological variation of the head and tail parts of the sperm, which do not meet the above criteria. There are many types of sperm “malformations”, which can occur in the head or tail alone, or in both the head and tail.  So, what is the value of sperm “malformation rate” to be considered normal? Many people may think that normal sperm should account for at least half of all sperm, otherwise how can they give birth normally, but in fact, the proportion of normal sperm is ≥ 4%, that is, as long as the sperm “malformation rate” is ≤ 96%. Clinically, many patients are overwhelmed by a routine semen examination that indicates a sperm “malformation rate” of >96%. In fact, there is no need to be so nervous because each semen specimen used in a routine semen examination is just a small sample taken from all your semen, so there may be sampling errors. At this point, it is recommended that you have a new semen routine done to clarify the diagnosis.  If your semen test repeatedly indicates an increase in sperm “malformation rate”, your semen is really problematic, which may lead to male infertility, affect the quality of embryos and increase the risk of female miscarriage. Generally speaking, increased sperm “malformation rate” is associated with testicular sperm production dysfunction, genitourinary tract infection, varicocele, epididymal tuberculosis, radiation exposure, long-term sitz bath, long-term smoking and alcohol abuse, and environmental pollution. Therefore, if the cause of the increased sperm “malformation rate” can be identified, targeted treatment can be provided. However, clinically, many patients with increased sperm “malformation rate” do not have a clear cause. For these patients, in addition to improving their lifestyle habits, staying away from dangerous environments, eliminating bad habits, and paying attention to dietary adjustments, they can routinely supplement some trace elements with antioxidant effects, in addition, they can also choose Chinese medicine to regulate.