Is there a relationship between sperm malformation rate and baby malformation?

There are three main parameters of semen routine: sperm concentration, motility and sperm morphology. The latest 5th edition of the WHO semen manual stipulates the lower limit of normal semen reference values: total sperm count ≥ 39 million/mL, sperm concentration > 15 million/mL; total sperm motility ≥ 40%, sperm survival rate ≥ 58%; normal morphology sperm ≥ 4%. Many patients in the clinic have normal semen indicators, but the normal sperm morphology indicators do not meet the standard, causing patients to wonder whether they can get pregnant now. Will the baby born after pregnancy have deformities? Personally, I think the answer is no. Regarding the reference range of sperm morphology, it has been changing in recent years with the continuous revision of the WHO semen manual: the 3rd edition of the WHO manual should account for more than 30% of normal morphology; the 4th edition of the WHO manual should account for more than 15% of normal morphology; the 5th edition of the WHO manual should account for more than 4% of normal morphology. Is it because the quality of our semen has been declining in recent years? No, it is just like a student’s examination, when the teacher makes the questions difficult, the student’s examination score will become lower, by the same token, the morphology standard is becoming stricter and stricter, the patient’s morphology result will become lower and lower; the 5th edition manual is very strict for morphology, while the 4th edition manual mostly uses machine rather than manual method to detect morphology, the error is larger, the manual recommends to check more than 200 sperm to reflect the semen specimen Morphology rate; morphology has a greater reference significance for sperm selection in assisted reproduction techniques. Morphology is mainly related to the probability of pregnancy and has little to do with the nature of the sperm (genetic material), just as there is no direct relationship between human appearance and human nature, so patients with aberrant spermatozoa should not worry too much. The parameters of the semen routine are only a matter of assessing the probability of pregnancy, not a matter of being able or unable to conceive, nor can they predict the quality of embryos, etc. It is recommended that patients with teratozoospermia actively maintain healthy habits, quit smoking and smoking, take appropriate physical exercise, eat more foods with vitamin E and C such as kiwi and orange, and foods containing zinc such as beans and apples, to maintain a balanced nutrition and actively assist in pregnancy.