A normal rate of less than 4% is considered aberrant spermatozoa. According to the latest standards, spermatozoa with a normal morphology rate of less than 4% by rigorous sperm morphological staining analysis are considered teratozoospermia. Under normal circumstances, spermatozoa are tadpole-shaped in appearance, including the head, neck and tail. Like the existence of people with disabilities in society, human sperm can develop abnormally and appear oddly under the microscope, such as a head that is too small and a curled tail. Deformed sperm may have a defective fertilization function that makes it difficult to fertilize an egg. In fact, most of the sperm in normal male ejaculate are deformed, and only a small percentage of sperm are normal in shape. If there are too many deformed sperm, the proportion of “competitive” normal sperm will be significantly reduced, which will affect the overall “fighting power” of the sperm and will not help the sperm to successfully “capture” the egg. This affects the overall “fighting power” of the sperm, which is not conducive to the successful “capture” of the egg by the sperm, thus affecting the fertilization ability of the sperm. If the sperm deformity rate is too high, the male fertility will be low, making it difficult for the woman to get pregnant. Research shows that reproductive gland infections and inflammation (epididymitis, orchitis, prostatitis or vesiculitis), endocrine disorders, chromosomal abnormalities and other diseases, as well as smoking, alcoholism, late nights, high work pressure, high temperature work environment, high radiation environment and other bad habits and living environment are the causes of teratospermia. The majority of patients with deformed sperm can be fertile Modern medicine has been able to enable most patients with deformed sperm to be fertile. The combination of Chinese and Western medicine and medication with life care can enable some patients to reduce their sperm malformation rate and obtain natural fertility. According to Chinese medicine, kidney deficiency, damp-heat injection or concomitant stagnation are the pathological basis of excessive deformed spermatozoa, which can be treated with Chinese herbs or proprietary Chinese medicines. Western medicine commonly uses antibiotics, antioxidant drugs, anti-estrogen drugs and trace elements to treat teratozoospermia. However, some patients with teratozoospermia have difficulty in reducing sperm malformation rate and natural fertility through the above treatments and need to obtain fertility through assisted reproductive technology. Patients with mild to moderate azoospermia can have children through artificial insemination and first-generation in vitro fertilization (IVF), while patients with severe and very severe azoospermia require second-generation in vitro fertilization (ICSI), which stands for intracytoplasmic single sperm injection and involves the injection of a single sperm directly into the plasma of the oocyte for fertilization with the help of a microscopic operating system. The severity of teratozoospermia does not affect the success rate of second generation IVF. As long as the internal quality of the sperm is good, some extremely severe cases of teratozoospermia (sperm malformation rate as high as 100%) can achieve a high fertility success rate with second-generation IVF technology. Fetal malformation and sperm malformation are not the same thing Will a high sperm malformation rate cause fetal malformation? Will it be easy to miscarry? In fact, fetal malformation and sperm malformation are not the same thing. Sperm malformation is only an abnormal shape that affects the ability to fertilize, while the intrinsic quality of sperm is the main factor that affects the quality of the embryo and miscarriage. However, some patients with teratozoospermia have high sperm DNA fragmentation rate, chromosomal abnormalities and other diseases, which can cause higher miscarriage and fetal abnormality rates. Fetal malformations occur mainly in the early stages of a woman’s pregnancy (within the first trimester). If during this period, the pregnant woman is infected with pathogens, has a fever, takes harmful drugs (antibiotics, hormones, neurotoxic drugs, etc.), or is exposed to environmental risk factors (alcoholism, pesticides, radiation), it will directly endanger the development of fetal organs, leading to fetal malformation or developmental delay and easy miscarriage. Thus, it seems that fetal malformation and sperm malformation are not necessarily related.