1. Symptoms of malignant tumor bone metastasis are characterized by a pain, which is aggravated after activity or exertion, such as coughing, stooling with force, joint movement to a certain position, etc. It is heavy at night and aggravated on rainy days; b Pain is not necessarily positively correlated with the degree of bone destruction; light destruction does not necessarily mean light pain or asymptomatic, heavy destruction does not necessarily mean heavy pain; c In addition to pain, severe cases may lead to pathological fracture, joint movement disorder, paraplegia, etc.; 2, Diagnosis of malignant tumor bone metastases a Clear diagnosis of primary disease of malignant tumor, or bone metastases with biopsy pathology b ECT whole-body bone imaging can complete the whole-body skeletal examination at one time, which can be used for pre-treatment assessment, in-treatment or post-treatment review, and can clarify the scope of whole-body bone metastases, which can diagnose bone metastases earlier than CT and plain film, but cannot clarify the degree of destruction, and sometimes need to combine with CT, MRI and plain film to diagnose bone metastases, and exclude c MRI is the most accurate and earliest means to diagnose bone metastasis, and it can clarify the extent of bone destruction at the examination site, but the disadvantage is that it needs to be examined by site. 3.Bone metastasis radiotherapy for malignant tumors a. To control local tumors, relieve pain, reduce the risk of serious bone events, such as pathological fracture and paraplegia, and improve the quality of life of patients with advanced disease; b. To select the site with obvious pain, activity or weight-bearing for radiotherapy according to the condition; c. To cooperate with other treatments to improve the effect of bone metastasis treatment. 4. Precautions for bone metastases from malignant tumors a. Avoid improper movement or exertion of metastatic bones, the amplitude, speed and strength should be small and slow, not suitable for massage or massage, serious cases should be: avoid extra weight-bearing for spinal metastases, axial turning is required, simply put, don’t bend and don’t rotate, overall turning, vertical rising and falling, avoiding leverage to aggravate the injury; lumbar metastases should lie flat, keep the bowels open, do less bending The cervical metastasis should wear a neck brace; the hip or femur should avoid climbing the stairs and need crutches or wheelchair to travel; b Regularly apply zoledronic acid treatment, either once a month or once every 3 months, or once every 3 months after 1 year of monthly application; if necessary, calcium and vitamin D3 can be supplemented; stop taking calcium 48 hours before and after applying zoledronic acid; check the kidney function and blood calcium before each application of zoledronic acid. 5.Other treatments for malignant tumor bone metastases a Radionuclide therapy, such as strontium 89, samarium 153, etc., belongs to the etiological treatment, which is suitable for systemic multiple bone metastases, especially osteogenic metastases, those who are phenomenal on ECT, need to be applied once every 3-6 months, which has a greater impact on hematopoietic function, i.e., white blood cells, platelets, hemoglobin, especially those who are applied several times; b Bone cement or internal fixation, which is symptomatic treatment c chemotherapy or endocrine therapy, which works systemically, but the efficiency is generally low.