What are the side effects of NSAIDs on other organs?

  In addition to the side effects on the gastrointestinal tract and kidneys, NSAIDs have certain side effects on other organs of electricity.  Some NSAIDs can produce mild neurological side effects, with common symptoms such as headache; dizziness, tinnitus, insomnia, and abnormal sensation. Delirium, convulsions, coma and other serious symptoms can occur in cases of poisoning. NSAIDs also have certain effects on the hematological system, with granulocytopenia and aplastic anemia being the most common.  Higher doses of salicylic acid preparations can inhibit platelet agglutination and reduce their ability to adhere to each other, thereby prolonging bleeding time. Severe bleeding can often be induced in the presence of coexisting vascular lesions, and should be used with caution, especially in the presence of cerebrovascular lesions.  When using anticoagulation therapy for patients with artificial heart valves or vascular embolism, NSAIDs should be reduced to prevent major bleeding. Salicylates should be used with caution in patients with liver damage, vitamin deficiency, and before surgery. Aspirin, anti-inflammatory pain and other NSAIDs can have liver damage, and the common symptoms are xanthogranuloma, elevated transaminases, nausea and vomiting. In addition, rash and allergic reactions are not uncommon, and severe allergic reactions can even lead to asthma and shock. In case of the above, the patient should be sent to hospital quickly for rescue.