Antipyretics are commonly used medicines at home. Although febrifuge is commonly used, these drugs have certain side effects. Currently the antipyretics commonly used in pediatrics are acetaminophen-based (paracetamol, ibuprofen, acetylsalicylic acid (aspirin), indomethacin (anti-inflammatory pain), and mixtures of the above drugs. The first two are preferred for use, and the latter two may be used in specific conditions (e.g., Kawasaki disease, rheumatic diseases, and allergic diseases). The side effects seen are often gastrointestinal irritation, which in children can manifest as epigastric discomfort, nausea, and vomiting. These adverse phenomena can be alleviated by taking the drug after eating properly. What is a reasonable application? ● First of all, when the child’s temperature is higher than 38.5 ℃, or the temperature is not very high, but the child child has a history of febrile convulsions, then need to apply antipyretics. Because high fever will bring many adverse effects to children, the appropriate application of antipyretics can reduce the body metabolic rate of febrile children, increase the comfort of the child, avoid the occurrence of febrile convulsions, and is conducive to the treatment of the primary disease. Currently, pediatric antipyretics promoted by the World Health Organization are acetaminophen-based and ibuprofen-based. The latter has a longer duration of action, and alternating between the two can reduce the number of doses and be more effective. Before using antipyretics on your child, read the ingredients. Allow at least 4 hours between doses of the same antipyretic. If your child’s temperature rises above 38.5°C soon after taking an antipyretic, and the time between fevers is less than 4 hours, take an antipyretic with another ingredient. This will reduce the number of times each medication is used in a 24-hour period and will also reduce the side effects of the medication. ● The dose of antipyretic to be applied is related to the age and weight of the child, not to the degree of fever. Do not blindly increase the dose. Taking too much antipyretic can cause the child to sweat profusely, have a rapid drop in body temperature, and suffer from weakness or even convulsions, causing undue damage to the child. Do not apply antipyretics containing the same ingredient at the same time. ● After using antipyretics, the pediatrician’s body temperature will drop to varying degrees. After the body temperature is lowered, the child’s mental condition will also improve, but this does not mean that the child’s condition is also improving. Generally speaking, the efficacy of a single dose of antipyretic can only be maintained for 3-4 hours. If the disease is not under control, the temperature will rise again after 3-4 hours. If the temperature rises again to about 39 degrees, take another antipyretic. Antipyretics are not a cure-all. It is not true that the temperature will drop from high to normal and will not rise again once antipyretics are used for any cause of fever. Fever reducers work only to lower the temperature temporarily, and it is not possible to lower the temperature completely to normal. Babies under 3 months old, especially newborns, should not blindly take antipyretics, because the thermoregulatory center is not yet well developed, and the sweat glands of newborns are not yet developed, so antipyretics can not play much of a role, and sometimes will cause defecation instead. For infants under 3 months, it is best to use only physical cooling methods. Baby fever medication, be sure to follow the doctor’s instructions.